Ace the 2026 Occupational & Environmental Health Quiz – Master Disease & Injury Prevention!

It is difficult to calculate the biological half-life of a compound with ongoing exposure because, as exposure to the compound continues, the substance is continuously being added to the body. Therefore, it becomes challenging to measure the exact amount of the compound in the body and accurately determine its half-life. The other options, such as fluctuations in the body's metabolic rate or difficulty in measuring exposure, do not directly affect the calculation of the biological half-life and are not as critical as the continuous addition of the substance to the body.